Article

Alternative protocols of tissue fixation dramatically reduces the impact of DNA artifacts, unraveling the interpretation of clinical Comprehensive Genomic Profiling

2023-06-19

Abstract excerpt

<h4>ABSTRACT</h4> Formalin-fixed-paraffin-embedded (FFPE) samples represent the cornerstone of tissue-based analysis in precision medicine. Targeted next-generation sequencing (NGS) panels are routinely used to analyze a limited number of genes to guide treatment decision making for advanced stage patients. The number and complexity of genetic alterations to be investigated are rapidly growing, in several instance...

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Literature Corpus work: 30329a15-a178-58a0-9f2c-a4c91df96b9f
DOI: 10.1101/2023.06.17.23291533

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