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Innovative paraffin embedding to unlock archival blocks for highly demanding genomic analyses

2026-02-13

Abstract excerpt

<title>Abstract</title> <p>DNA analysis from formalin-fixed paraffin-embedded (FFPE) tissues is frequently compromised by fragmentation and fixation-induced artifacts, limiting advanced genomic applications. While fixation chemistry has been extensively studied, the contribution of paraffin embedding to DNA damage remains poorly defined. Here, starting from a direct experimental observation of embedding-associate...

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Literature Corpus work
e56d5a0a-cf1b-5a52-b1af-fc5f83ef0922
DOI
10.21203/rs.3.rs-8787286/v1
Open publication

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Innovative paraffin embedding to unlock archival blocks for highly demanding genomic analysesDOI 10.21203/rs.3.rs-8787286/v1
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