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Article

Exploring the shared genetic basis of major depressive disorder and frailty.

Journal of affective disorders - 1 Dec 2024

Fu Wei, Xu Rong, Bian Peiyu, Li Xu, Yang Kaikai, Wang Xiaoming

Abstract excerpt

BACKGROUND: Major depressive disorder (MDD) and frailty impose substantial health and economic burdens. MDD is recognized as a significant risk factor for frailty, but the genetic associations between these conditions remain unclear. This study investigates the genetic correlation, shared pleiotropic loci, causal relationships, and comorbid genes between MDD and frailty. METHODS: The genetic correlation between...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39214376
DOI: 10.1016/j.jad.2024.08.177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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