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A genome‐wide association study of the frailty index highlights brain pathways in ageing

25 Aug 2021

Abstract excerpt

Abstract Frailty is a common geriatric syndrome and strongly associated with disability, mortality and hospitalization. Frailty is commonly measured using the frailty index (FI), based on the accumulation of a number of health deficits during the life course. The mechanisms underlying FI are multifactorial and not well understood, but a genetic basis has been suggested with heritability estimates between 30 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 34431594
DOI: 10.1111/acel.13459

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