Article
A Genome-Wide Association Study of the Frailty Index Highlights Synaptic Pathways in Aging
2019-09-25
Abstract excerpt
<h4>ABSTRACT</h4> Frailty is a common geriatric syndrome, strongly associated with disability, mortality and hospitalisation. The mechanisms underlying frailty are multifactorial and not well understood, but a genetic basis has been suggested with heritability estimates between 19 and 45%. Understanding the genetic determinants and biological mechanisms underpinning frailty may help to delay or even prevent frailt...
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Identifiers and source
- Literature Corpus work
- 1d65af05-78aa-5448-9fdc-fd4bba52c2f4
- DOI
- 10.1101/19007559