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Article

Multilayer Genomic Characterization of a Shared Genetic Factor Linking Depression-Related Liability and Reduced Physical Function.

Genes - 16 Jul 2026

Zeng Wen, Yang Xiupeng, Xu Yonggang

Abstract excerpt

Background: Depression-related liability is frequently accompanied by reduced physical function, yet the shared genetic architecture linking mood-related traits and physical-function decline remains incompletely characterized. Methods: We applied genomic structural equation modeling to European-ancestry GWAS summary statistics for five constituent phenotypes: depressive symptoms, depression diagnosis, grip...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Source

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Identifiers

PMID: 42510853
DOI: 10.3390/genes17070813
PMCID: PMC13409734

Genes

CENPW
DCAF16
DRD2
FAM120A
NCAPG
SGIP1
TMEM106B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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