Article
Detection of multidrug-resistance in Mycobacterium tuberculosis by phenotype- and molecular-based assays.
Annals of clinical microbiology and antimicrobials - 28 Aug 2024
Vasiliauskaitė Laima, Bakuła Zofia, Vasiliauskienė Edita, Bakonytė Daiva, Decewicz Przemysław, Dziurzyński Mikołaj, Proboszcz Małgorzata, Davidavičienė Edita Valerija, Nakčerienė Birutė, Krenke Rafał, Kačergius Tomas, Stakėnas Petras, Jagielski Tomasz
Abstract excerpt
BACKGROUND: The whole-genome sequencing (WGS) is becoming an increasingly effective tool for rapid and accurate detection of drug resistance in Mycobacterium tuberculosis complex (MTBC). This approach, however, has still been poorly evaluated on strains from Central and Eastern European countries. The purpose of this study was to assess the performance of WGS against conventional drug susceptibility testing (DST)...
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