Article
Whole genome sequencing of multidrug-resistant Mycobacterium tuberculosis isolates collected in the Czech Republic, 2005-2020.
Scientific reports - 3 May 2022
Dohál Matúš, Dvořáková Věra, Šperková Miluše, Pinková Martina, Spitaleri Andrea, Norman Anders, Cabibbe Andrea Maurizio, Rasmussen Erik Michael, Porvazník Igor, Škereňová Mária, Solovič Ivan, Cirillo Daniela Maria, Mokrý Juraj
Abstract excerpt
The emergence and spread of resistant tuberculosis (TB) pose a threat to public health, so it is necessary to diagnose the drug-resistant forms in a clinically short time frame and closely monitor their transmission. In this study, we carried out a first whole genome sequencing (WGS)-based analysis of multidrug resistant (MDR) M. tuberculosis strains to explore the phylogenetic lineages diversity, drug resistance...
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