Article
Applying whole genome sequencing to predict phenotypic drug resistance in Mycobacterium tuberculosis: leveraging 20 years of nationwide data from Denmark.
Antimicrobial agents and chemotherapy - 7 Aug 2024
Kurtzhals Mads Lindholm, Norman Anders, Svensson Erik, Lillebaek Troels, Folkvardsen Dorte Bek
Abstract excerpt
Infection with Mycobacterium tuberculosis remains one of the biggest causes of death from a single microorganism worldwide, and the continuous emergence of drug resistance aggravates our ability to cure the disease. New improved resistance detection methods are needed to provide adequate treatment, such as whole genome sequencing (WGS), which has been used increasingly to identify resistance-conferring mutations...
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