Article
Whole genome sequencing of Mycobacterium tuberculosis for detection of drug resistance: a systematic review.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases - 1 Feb 2017
Papaventsis D, Casali N, Kontsevaya I, Drobniewski F, Cirillo D M, Nikolayevskyy V
Abstract excerpt
OBJECTIVES: We conducted a systematic review to determine the diagnostic accuracy of whole genome sequencing (WGS) of Mycobacterium tuberculosis for the detection of resistance to first- and second-line anti-tuberculosis (TB) drugs. METHODS: The study was conducted according to the criteria of the Preferred Reporting Items for Systematic Reviews group. A total of 20 publications were included. The sensitivity,...
Topics
- Antitubercular Agents
- Drug Resistance, Bacterial
- Genes, Bacterial
- Genome, Bacterial
- Genomics
- Humans
- Mutation
- Mycobacterium tuberculosis
- Phylogeny
- Polymorphism, Genetic
