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Article

Assessing contributions of DNA sequences at the 3' end of a yeast gene on yFACT, RNA polymerase II, and nucleosome occupancy.

BMC research notes - 6 Aug 2024

Byrd Samuel E, Hoyt Brianna, Ozersky Sydney A, Crocker Alex W, Habenicht Daniel, Nester Mattie R, Prowse Heather, Turkal Claire E, Joseph Lauren, Duina Andrea A

Abstract excerpt

OBJECTIVE: In past work in budding yeast, we identified a nucleosomal region required for proper interactions between the histone chaperone complex yFACT and transcribed genes. Specific histone mutations within this region cause a shift in yFACT occupancy towards the 3' end of genes, a defect that we have attributed to impaired yFACT dissociation from DNA following transcription. In this work we wished to assess...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39103906
DOI: 10.1186/s13104-024-06872-y
PMCID: PMC11301940

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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