Article
Genetic interactions between POB3 and the acetylation of newly synthesized histones.
Current genetics - 1 Aug 2011
Nair Devi M, Ge Zhongqi, Mersfelder Erica L, Parthun Mark R
Abstract excerpt
Pob3p is an essential component of the S. cerevisiae FACT complex (yFACT). Several lines of evidence indicate that the yFACT complex plays an important role in chromatin assembly including the observation that the pob3 Q308K allele is synthetically lethal with an allele of histone H4 that prevents the diacetylation of newly synthesized molecules. We have analyzed the genetic interactions between the Q308K allele...
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