Article
Charged residues on the side of the nucleosome contribute to normal Spt16-gene interactions in budding yeast.
Epigenetics - 1 Jan 2018
Nyamugenda Eugene, Cox A Brandon, Pierce Jacob B, Banning Ryan C, Huynh Michelle L, May Catey, Marshall Sarah, Turkal Claire E, Duina Andrea A
Abstract excerpt
Previous work in Saccharomyces cerevisiae identified three residues located in close proximity to each other on the side of the nucleosome whose integrity is required for proper association of the Spt16 component of the FACT complex across transcribed genes. In an effort to gain further insights into the parameters that control Spt16 interactions with genes in vivo, we tested the effects of additional histone...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
