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Epigenetic Association Analyses and Risk Prediction of RLS

22 May 2023

Abstract excerpt

BACKGROUND: As opposed to other neurobehavioral disorders, epigenetic analyses and biomarkers are largely missing in the case of idiopathic restless legs syndrome (RLS). OBJECTIVES: Our aims were to develop a biomarker for RLS based on DNA methylation in blood and to examine DNA methylation in brain tissues for dissecting RLS pathophysiology. METHODS: Methylation of blood DNA from three independent cohorts (n =...

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PMID: 37212434
DOI: 10.1002/mds.29440

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