Article
Identification of Restless Legs Syndrome Genes by Mutational Load Analysis.
Annals of neurology - 1 Feb 2020
Tilch Erik, Schormair Barbara, Zhao Chen, Salminen Aaro V, Antic Nikolic Ana, Holzknecht Evi, Högl Birgit, Poewe Werner, Bachmann Cornelius G, Paulus Walter, Trenkwalder Claudia, Oertel Wolfgang H, Hornyak Magdolna, Fietze Ingo, Berger Klaus, Lichtner Peter, Gieger Christian, Peters Annette, Müller-Myhsok Bertram, Hoischen Alexander, Winkelmann Juliane, Oexle Konrad
Abstract excerpt
OBJECTIVE: Restless legs syndrome is a frequent neurological disorder with substantial burden on individual well-being and public health. Genetic risk loci have been identified, but the causatives genes at these loci are largely unknown, so that functional investigation and clinical translation of molecular research data are still inhibited. To identify putatively causative genes, we searched for highly...
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