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Comparative essentialome analysis of six <i>Pectobacteriaceae</i> strains using the TNSEEK pipeline identifies conserved and strain-specific fitness determinants

2025-12-12

Abstract excerpt

<h4>Summary</h4> Transposon sequencing (Tn-seq) is a powerful technique for defining the essential genes required for bacterial survival. However, gene essentiality can vary significantly across taxonomic levels, and comparing large Tn-seq datasets from multiple strains presents considerable analytical challenges. To address this, we developed TNSEEK, a fully automated bioinformatics pipeline for the systematic a...

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Literature Corpus work
f47e2544-19e7-5379-be05-1f49f8c62f1c
DOI
10.64898/2025.12.09.693261
Open publication

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Comparative essentialome analysis of six <i>Pectobacteriaceae</i> strains using the TNSEEK pipeline identifies conserved and strain-specific fitness determinantsDOI 10.64898/2025.12.09.693261
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