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Article

The impact of genetic diversity on gene essentiality within the Escherichia coli species.

Nature microbiology - 1 Mar 2021

Rousset François, Cabezas-Caballero Jose, Piastra-Facon Florence, Fernández-Rodríguez Jesús, Clermont Olivier, Denamur Erick, Rocha Eduardo P C, Bikard David

Abstract excerpt

Bacteria from the same species can differ widely in their gene content. In Escherichia coli, the set of genes shared by all strains, known as the core genome, represents about half the number of genes present in any strain. Although recent advances in bacterial genomics have unravelled genes required for fitness in various experimental conditions, most studies have focused on single model strains. As a result,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 33462433
DOI: 10.1038/s41564-020-00839-y

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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