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Comparative Tn-Seq reveals common daptomycin resistance determinants in <i>Staphylococcus aureus</i> despite strain-dependent differences in essentiality of shared cell envelope genes

2019-05-23

Abstract excerpt

Antibiotic-resistant Staphylococcus aureus remains a leading cause of antibiotic resistance-associated mortality in the United States. Given the reality of multi-drug resistant infections, it is imperative that we establish and maintain a pipeline of new compounds to replace or supplement our current antibiotics. A first step towards this goal is to prioritize targets by identifying the genes most consistently re...

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Literature Corpus work
d26bbad5-a285-5b5c-90da-4abed3fe6bd6
DOI
10.1101/648246
Open publication

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Comparative Tn-Seq reveals common daptomycin resistance determinants in <i>Staphylococcus aureus</i> despite strain-dependent differences in essentiality of shared cell envelope genesDOI 10.1101/648246
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