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Article

Defining the ABC of gene essentiality in streptococci.

BMC genomics - 31 May 2017

Charbonneau Amelia R L, Forman Oliver P, Cain Amy K, Newland Graham, Robinson Carl, Boursnell Mike, Parkhill Julian, Leigh James A, Maskell Duncan J, Waller Andrew S

Abstract excerpt

BACKGROUND: Utilising next generation sequencing to interrogate saturated bacterial mutant libraries provides unprecedented information for the assignment of genome-wide gene essentiality. Exposure of saturated mutant libraries to specific conditions and subsequent sequencing can be exploited to uncover gene essentiality relevant to the condition. Here we present a barcoded transposon directed insertion-site...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28569133
DOI: 10.1186/s12864-017-3794-3
PMCID: PMC5452409

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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