Article
Chemical carcinogens and proto-oncogens activation.
Biochimie - 1 Jan 2000
Laval J, Strauss B S
Abstract excerpt
The induction of proto-oncogens H-ras-1 by nitrosomethylurea (Sukumar et al. (1983), 306, 658-661) is discussed in term of lack of DNA-repair of lesions induced in DNA by this alkylating agent, particularly O6-methylguanine residues and apurinic/apyrimidinic sites.
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