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Article

Proto-oncogene activation in rodent and human tumors.

Advances in experimental medicine and biology - 1 Jan 1991

Anderson M W, You M, Reynolds S H

Abstract excerpt

The transformation of a normal cell into a tumorigenic cell involves both the activation and concerted expression of proto-oncogenes and inactivation of suppressor genes. The activation of ras proto-oncogenes represents one step in the multistep process of carcinogenesis for a variety of rodent and human tumors. This activation is probably an early event in tumorigenesis in many cases and may be the 'initiation'...

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PMID: 2068988
DOI: 10.1007/978-1-4684-5877-0_23

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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