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Article

Proto-oncogene activation in rodent and human tumors.

Advances in experimental medicine and biology - 1 Jan 1991

Anderson M W, You M, Reynolds S H

Abstract excerpt

The transformation of a normal cell into a tumorigenic cell involves both the activation and concerted expression of proto-oncogenes and inactivation of suppressor genes. The activation of ras proto-oncogenes represents one step in the multistep process of carcinogenesis for a variety of rodent and human tumors. This activation is probably an early event in tumorigenesis in many cases and may be the 'initiation'...

Topics

Animals
Gene Expression Regulation
Humans
Lung Neoplasms
Mice
Mutation
Neoplasms
Proto-Oncogene Mas
Proto-Oncogenes

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2068988
DOI: 10.1007/978-1-4684-5877-0_23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2068988-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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