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Article

The role of non-ras transforming genes in chemical carcinogenesis.

Environmental health perspectives - 1 Jun 1991

Cooper C S

Abstract excerpt

DNA transfection experiments using the NIH 3T3 mouse fibroblast cell line have demonstrated that chemically induced tumors and chemically transformed cell lines frequently contain dominant transforming genes. Although many of the genes detected using the NIH 3T3 transfection-transformation assay are activated versions of H-ras, K-ras, and N-ras, in some experimental systems activated forms of genes such as met...

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Identifiers

PMID: 1685444
DOI: 10.1289/ehp.919333
PMCID: PMC1568034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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