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Article

Induction of ouabain-resistance mutation and cycle-dependent transformation of C3H/10T1/2 cells by N-nitroso-2-acetylaminofluorene.

Mutation research - 1 May 1990

Lin J K, Kuo M L

Abstract excerpt

Ouabain-resistance mutation and cell cycle-dependent transformation were studied concurrently in the C3H/10T1/2 cell line treated with N-nitroso-2-acetylaminofluorene (N-NO-AAF) or N-nitroso-N-2-fluorenylacetamide. N-NO-AAF is a new direct-acting mutagen that exhibits a very short half-life (34 m...

Topics

2-Acetylaminofluorene
Animals
Cell Cycle
Cell Division
Cell Line
Cell Survival
Cell Transformation, Neoplastic
Dose-Response Relationship, Drug
Drug Resistance
Half-Life
Mutagens
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Nitroso Compounds

Ouabain

Time Factors

Source

Identifiers

PMID: 2342496
DOI: 10.1016/0027-5107(90)90039-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-2342496-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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