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Article

Human cytochrome C natural variants: Studying the membrane binding properties of G41S and Y48H by fluorescence energy transfer and molecular dynamics.

International journal of biological macromolecules - 1 Aug 2024

Muroni Alessia, Minicozzi Velia, Piro Maria Cristina, Sinibaldi Federica, Mei Giampiero, Di Venere Almerinda

Abstract excerpt

Cytochrome C (cyt C), the protein involved in oxidative phosphorylation, plays several other crucial roles necessary for both cell life and death. Studying natural variants of cyt C offers the possibility to better characterize the structure-to-function relationship that modulates the different activities of this protein. Naturally mutations in human cyt C (G41S and Y48H) occur in the protein central Ω-loop and...

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Identifiers

PMID: 38914400
DOI: 10.1016/j.ijbiomac.2024.133371

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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