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Article

Influence of cysteine-directed mutations at the Ω-loops on peroxidase activity of human cytochrome c.

Archives of biochemistry and biophysics - 30 Sept 2021

Samsri Sasiprapa, Pornsuwan Soraya

Abstract excerpt

Cytochrome c (Cytc) is a multifunctional protein associated with electron shuttling in the inner membrane of mitochondria and also involving in the apoptotic pathway. It has been identified that mutations located in the flexible central 40-57 Ω-loop including the naturally occurring G41S, Y48H, and A51V mutants, which are found in patients with thrombocytopenia 4, a platelet disorder, alter the structural...

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Identifiers

PMID: 34224685
DOI: 10.1016/j.abb.2021.108980

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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