Article
Possibility of Cell Block Specimens from Overnight-Stored Bile for Next-Generation Sequencing of Cholangiocarcinoma.
Cells - 28 May 2024
Okuno Mitsuru, Kanayama Tomohiro, Iwata Keisuke, Tanaka Takuji, Tomita Hiroyuki, Iwasa Yuhei, Shirakami Yohei, Watanabe Naoki, Mukai Tsuyoshi, Tomita Eiichi, Shimizu Masahito
Abstract excerpt
The identification of anticancer therapies using next-generation sequencing (NGS) is necessary for the treatment of cholangiocarcinoma. NGS can be easily performed when cell blocks (CB) are obtained from bile stored overnight. We compared NGS results of paired CB and surgically resected specimens (SRS) from the same cholangiocarcinoma cases. Of the prospectively collected 64 bile CBs from 2018 to 2023, NGS was...
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