Article
Molecular profiling in cholangiocarcinoma: A practical guide to next-generation sequencing.
Cancer treatment reviews - 1 Jan 2024
Stenzinger Albrecht, Vogel Arndt, Lehmann Ulrich, Lamarca Angela, Hofman Paul, Terracciano Luigi, Normanno Nicola
Abstract excerpt
Cholangiocarcinomas (CCA) are a heterogeneous group of tumors that are classified as intrahepatic, perihilar, or distal according to the anatomic location within the biliary tract. Each CCA subtype is associated with distinct genomic alterations, including single nucleotide variants, copy number variants, and chromosomal rearrangements or gene fusions, each of which can influence disease prognosis and/or...
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