Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Single-cell Transcriptomic Architecture Unraveling the Complexity of Tumor Heterogeneity in Distal Cholangiocarcinoma

1 Jan 2022

Abstract excerpt

BACKGROUND & AIMS: Distal cholangiocarcinoma (dCCA) are a group of epithelial cell malignancies that occurs at the distal common bile duct, and account for approximately 40% of all cholangiocarcinoma cases. dCCA remains a highly lethal disease as it typically features remarkable cellular heterogeneity. A comprehensive exploration of cellular diversity and the tumor microenvironment is essential to depict the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer Immunotherapy and Biomarkers
Share to Cholangiocarcinoma and Gallbladder Cancer Studies
Share to Single-cell and spatial transcriptomics

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35219893
DOI: 10.1016/j.jcmgh.2022.02.014

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Single-cell Transcriptomic Architecture Unraveling the Complexity of Tumor Heterogeneity in Distal CholangiocarcinomaPMID 35219893Read ↗

Unraveling the heterogeneity of cholangiocarcinoma and identifying biomarkers and therapeutic strategies with single-cell sequencing technologySemantic proximity Read ↗

Revealing the Heterogeneity of the Tumor Ecosystem of Cholangiocarcinoma through Single-Cell TranscriptomicsSemantic proximity Read ↗

Deciphering cholangiocarcinoma heterogeneity and specific progenitor cell niche of extrahepatic cholangiocarcinoma at single-cell resolutionSemantic proximity Read ↗

Single-Cell Transcriptome Analysis Identifies Novel Biomarkers Involved in Major Liver Cancer SubtypesSemantic proximity Read ↗

Single-cell transcriptomic architecture and intercellular crosstalk of human intrahepatic cholangiocarcinomaSemantic proximity Read ↗

Single-cell and spatial architecture of primary liver cancerSemantic proximity Read ↗

Single-Cell Transcriptomic Analysis Reveals Two Molecularly and Clinically Distinct Subtypes of Intrahepatic CholangiocarcinomaSemantic proximity Read ↗

Single-cell landscape of immunocytes in patients with extrahepatic cholangiocarcinomaSemantic proximity Read ↗

Single-cell analysis reveals heterogeneity in the molecular profile of the tumor microenvironment of biliary tract cancersSemantic proximity Read ↗

Single-cell RNA-seq highlights intra-tumoral heterogeneity and malignant progression in pancreatic ductal adenocarcinomaSemantic proximity Read ↗

Generation of a biliary tract cancer cell line atlas reveals molecular subtypes and therapeutic targetsSemantic proximity Read ↗

Establishment of a reference single-cell RNA sequencing dataset for human pancreatic adenocarcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.