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Article

Cancer related gene alterations can be detected with next-generation sequencing analysis of bile in diffusely infiltrating type cholangiocarcinoma.

Experimental and molecular pathology - 1 Aug 2016

Lee Chang Hun, Wang Hong En, Seo Seung Young, Kim Seong Hun, Kim In Hee, Kim Sang Wook, Lee Soo Teik, Kim Dae Ghon, Han Myung Kwan, Lee Seung Ok

Abstract excerpt

Genome-wide association study in diffusely infiltrating type cholangiocarcinoma (CC) can be limited due to the difficulty of obtaining tumor tissue. We aimed to evaluate the genomic alterations of diffusely infiltrating type CC using next-generation sequencing (NGS) of bile and to compare the variations with those of mass-forming type CC. A total of 24 bile samples obtained during endoscopic retrograde...

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Source

Identifiers

PMID: 27460275
DOI: 10.1016/j.yexmp.2016.07.010

Genes

ABL1
APC
ATM
BRAF
EGFR
ERBB4
FGFR1
GNA11
GNAQ
IDH1
KDR
KRAS
SMAD4
SMO
STK11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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