Article
Update on cholangiocarcinoma: potential impact of genomic studies on clinical management.
Zeitschrift fur Gastroenterologie - 1 Jun 2017
Walter Dirk, Hartmann Sylvia, Waidmann Oliver
Abstract excerpt
The term cholangiocarcinoma (CCA) comprises neoplasms of the intrahepatic, perihilar, and distal bile duct. Five-year survival rates of patients with CCA are below 20 %, and no targeted therapy could prove a benefit in comparison to the standard treatment of cisplatinum and gemcitabine. In recent years, next generation sequencing studies revealed a profound genomic heterogeneity of CCA subtypes potentially...
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