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Article

Environmental stresses can alleviate the average deleterious effect of mutations.

Journal of biology - 1 Jan 2003

Kishony Roy, Leibler Stanislas

Abstract excerpt

BACKGROUND: Fundamental questions in evolutionary genetics, including the possible advantage of sexual reproduction, depend critically on the effects of deleterious mutations on fitness. Limited existing experimental evidence suggests that, on average, such effects tend to be aggravated under environmental stresses, consistent with the perception that stress diminishes the organism's ability to tolerate...

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Identifiers

PMID: 12775217
DOI: 10.1186/1475-4924-2-14
PMCID: PMC193686

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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