The spectrum of adaptive mutations in experimental evolution.

doi:10.1016/j.ygeno.2014.09.011

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Article

The spectrum of adaptive mutations in experimental evolution.

Genomics - 1 Dec 2014

Lang Gregory I, Desai Michael M

Abstract excerpt

A primary goal of recent work in experimental evolution is to probe the molecular basis of adaptation. This requires an understanding of the individual mutations in evolving populations: their identity, their physiological and fitness effects, and the interactions between them. The combination of...

Topics

Adaptation, Biological
Directed Molecular Evolution
Epistasis, Genetic
Evolution, Molecular
Genetic Fitness
High-Throughput Nucleotide Sequencing
Mutation

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