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Cleave and Rescue gamete killers create conditions for gene drive in plants.

Nature plants - 1 Jun 2024

Oberhofer Georg, Johnson Michelle L, Ivy Tobin, Antoshechkin Igor, Hay Bruce A

Abstract excerpt

Gene drive elements promote the spread of linked traits and can be used to change the composition or fate of wild populations. Cleave and Rescue (ClvR) drive elements sit at a fixed chromosomal position and include a DNA sequence-modifying enzyme such as Cas9/gRNAs that disrupts endogenous versions of an essential gene and a recoded version of the essential gene resistant to cleavage. ClvR spreads by creating...

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PMID: 38886522
DOI: 10.1038/s41477-024-01701-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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