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Article

Split versions of Cleave and Rescue selfish genetic elements for measured self limiting gene drive.

PLoS genetics - 1 Feb 2021

Oberhofer Georg, Ivy Tobin, Hay Bruce A

Abstract excerpt

Gene drive elements promote the spread of linked traits, providing methods for changing the composition or fate of wild populations. Drive mechanisms that are self-limiting are attractive because they allow control over the duration and extent of trait spread in time and space, and are reversible through natural selection as drive wanes. Self-sustaining Cleave and Rescue (ClvR) elements include a DNA...

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Identifiers

PMID: 33600432
DOI: 10.1371/journal.pgen.1009385
PMCID: PMC7951863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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