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Article

Shared genetic effect of kidney function on bipolar and major depressive disorders: a large-scale genome-wide cross-trait analysis.

Human genomics - 11 Jun 2024

Yu Simin, Lin Yifei, Yang Yong, Jin Xi, Liao Banghua, Lu Donghao, Huang Jin

Abstract excerpt

BACKGROUND: Epidemiological studies have revealed a significant association between impaired kidney function and certain mental disorders, particularly bipolar disorder (BIP) and major depressive disorder (MDD). However, the evidence regarding shared genetics and causality is limited due to residual confounding and reverse causation. METHODS: In this study, we conducted a large-scale genome-wide cross-trait...

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Source

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Identifiers

PMID: 38858783
DOI: 10.1186/s40246-024-00627-3
PMCID: PMC11165782

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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