Article
A genomewide linkage scan of cocaine dependence and major depressive episode in two populations.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Nov 2011
Yang Bao-Zhu, Han Shizhong, Kranzler Henry R, Farrer Lindsay A, Gelernter Joel
Abstract excerpt
Cocaine dependence (CD) and major depressive episode (MDE) frequently co-occur with poorer treatment outcome and higher relapse risk. Shared genetic risk was affirmed; to date, there have been no reports of genomewide linkage scans (GWLSs) surveying the susceptibility regions for comorbid CD and MDE (CD-MDE). We aimed to identify chromosomal regions and candidate genes susceptible to CD, MDE, and CD-MDE in...
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