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Genetic analyses in UK Biobank identifies 78 novel loci associated with urinary biomarkers providing new insights into the biology of kidney function and chronic disease

2018-05-05

Abstract excerpt

<h4>Background</h4> Urine biomarkers, such as creatinine, microalbumin, potassium and sodium are strongly associated with several common diseases including chronic kidney disease, cardiovascular disease and diabetes mellitus. Knowledge about the genetic determinants of the levels of these biomarker may shed light on pathophysiological mechanisms underlying the development of these diseases. <h4>Methods</h4> We p...

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Literature Corpus work
e34f9330-e719-5f2b-8124-f4a1c5716b56
DOI
10.1101/315259
Open publication

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Genetic analyses in UK Biobank identifies 78 novel loci associated with urinary biomarkers providing new insights into the biology of kidney function and chronic diseaseDOI 10.1101/315259
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