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Article

Shared Genetics of Kidney Function Traits and Bladder Cancer: A Genome-Wide Cross-Trait Analysis.

Cancer medicine - 1 Jul 2026

Lin Yifei, Xiang Nanyan, Yang Yong, Huang Shujun, Su Shiqi, Fu Tingting, Luo Yurui, Wang Zeng, Shi Rui, Zheng Tao, Liao Banghua, Huang Jin

Abstract excerpt

BACKGROUND: Clinical and epidemiological evidence has suggested a potential association between kidney dysfunction and bladder cancer (BC). One hypothesis for this comorbidity is the presence of a common genetic etiology. However, little is known about the shared genetics and causality of this association. Thus, we aimed to investigate shared genetic architecture and the causal link between kidney dysfunction and...

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Share to Genetic Predisposition to Disease
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Kidney Diseases

Share to Linkage Disequilibrium

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Share to Quantitative Trait Loci

Share to Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 42470241
DOI: 10.1002/cam4.72025
PMCID: PMC13379772

Genes

ATP2A1
PSCA
ZFHX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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