Article
Comparison of heritability of Cystatin C- and creatinine-based estimates of kidney function and their relation to heritability of cardiovascular disease.
Journal of the American Heart Association - 14 Jan 2015
Arpegård Johannes, Viktorin Alexander, Chang Zheng, de Faire Ulf, Magnusson Patrik K E, Svensson Per
Abstract excerpt
BACKGROUND: Decreased renal function is an established risk factor for cardiovascular disease (CVD). Causal mechanisms between estimates of renal function and CVD are intricate and investigation of the relative importance of genetic and environmental factors for the variability of these phenotypes could provide new knowledge. METHODS AND RESULTS: Cystatin C and creatinine levels in 12 313 twins were analyzed....
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