Article
Adaptive immune receptor germline gene variation.
Current opinion in immunology - 1 Apr 2024
Corcoran Martin M, Karlsson Hedestam Gunilla B
Abstract excerpt
Recognition of antigens by T cell receptors (TCRs) and B cell receptors (BCRs) is a key step in lymphocyte activation. T and B cells mediate adaptive immune responses, which protect us against infections and provide immunological memory, and also, in some instances, drive pathogenic responses in autoimmune diseases. TCRs and BCRs are encoded within loci that are known to be genetically diverse. However, the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
