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The current landscape of adaptive immune receptor genomic and repertoire data: OGRDB and VDJbase

6 Nov 2025

Abstract excerpt

Accurate characterization of adaptive immune receptor repertoires through high-throughput sequencing is critical for understanding immune responses, disease biomarkers, vaccine design, and antibody engineering. However, progress depends on precise knowledge of germline reference sequences, which are challenging to define due to extensive allelic variation and structural complexity in immunoglobulin and T cell...

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PMID: 41206474
DOI: 10.1093/nar/gkaf1094

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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