Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human adaptive immune receptor repertoire analysis-Past, present, and future.

Immunological reviews - 1 Jul 2018

Nielsen Sandra C A, Boyd Scott D

Abstract excerpt

The genes encoding adaptive immune antigen receptors, namely the immunoglobulins expressed in membrane-bound or secreted forms by B cells, and the cell surface T cell receptors, are unique in human biology because they are generated by combinatorial rearrangement of the genomic DNA. The diversity of receptors so generated in populations of lymphocytes enables the human immune system to recognize antigens...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptive Immunity
Share to Antibodies
Share to Autoimmunity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to B-Lymphocytes

Share to High-Throughput Nucleotide Sequencing

Share to Hypersensitivity

Share to Receptors, Antigen, T-Cell

Share to V(D)J Recombination

Source

Identifiers

PMID: 29944765
DOI: 10.1111/imr.12667

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human adaptive immune receptor repertoire analysis-Past, present, and future.PMID 29944765Read ↗

T-Cell Receptor Repertoire Sequencing and Its Applications: Focus on Infectious Diseases and CancerSemantic proximity Read ↗

The current landscape of adaptive immune receptor genomic and repertoire data: OGRDB and VDJbaseSemantic proximity Read ↗

Assessing human B cell repertoire diversity and convergence.Semantic proximity Read ↗

Reading the repertoire: Progress in adaptive immune receptor analysis using machine learningSemantic proximity Read ↗

High-throughput sequencing of the T-cell receptor repertoire: pitfalls and opportunities.Semantic proximity Read ↗

Alternative mechanisms of immune receptor diversity.Semantic proximity Read ↗

The human T‐cell receptor repertoire in health and disease and potential for omics integrationSemantic proximity Read ↗

Unmasking Human T Cell Receptor Germline Diversity: 335 Novel Alleles Identified in 47 Pangenome Reference Individuals Using the gAIRR SuiteSemantic proximity Read ↗

Profiling Germline Adaptive Immune Receptor Repertoire with gAIRR SuiteSemantic proximity Read ↗

NGS-Based B-Cell Receptor Repertoire AnalysisRepertoire analyses in the Context of Inborn Errors of Immunity.Semantic proximity Read ↗

The Diagnostic, Prognostic, and Therapeutic Potential of Adaptive Immune Receptor Repertoire Profiling in CancerSemantic proximity Read ↗

Tissue determinants of the human T cell receptor repertoire.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.