TCR gene polymorphisms and autoimmune disease.

doi:10.1111/j.1744-313x.1996.tb00279.x

Article

TCR gene polymorphisms and autoimmune disease.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Apr 1996

Kay R A

Abstract excerpt

Autoimmunity may result from abnormal regulation within the immune system. As the T cell is the principal regulator of the immune system and its normal function depends on immune recognition or self/non-self discrimination, abnormalities of the idiotypic T-cell receptor (TCR) may be one cause of...

Topics

Alleles
Animals
Autoimmune Diseases
Gene Expression Regulation
Humans
Polymorphism, Genetic
Receptors, Antigen, T-Cell

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