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Omeprazole and risk of osteoarthritis: insights from a mendelian randomization study in the UK Biobank

27 May 2024

Abstract excerpt

BACKGROUND: A former cohort study has raised concern regarding the unanticipated hazard of omeprazole in expediting osteoarthritis (OA) advancement. The precise nature of their causal evidence, however, remains undetermined. The present research endeavors to investigate the underlying causal link between omeprazole and OA through the application of mendelian randomization (MR) analysis. METHODS: The study...

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PMID: 38802944
DOI: 10.1186/s12967-024-05255-y

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