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Exploring the Genetic Links Between Asthma, Gastroesophageal Reflux Disease, and Osteoarthritis Through Mendelian Randomization

2024-06-18

Abstract excerpt

<title>Abstract</title> <p>To elucidate the bidirectional associations and mechanisms linking the increasingly prevalent conditions of asthma, gastroesophageal reflux disease (GERD), and osteoarthritis (OA), with a focus on exploring the mediating role of Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) in these associations. Employing a comprehensive two-sample, bidirectional Mendelian randomization (MR) framework,...

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Literature Corpus work
a63bbe32-4fde-5d5a-9cba-06f60e1988b3
DOI
10.21203/rs.3.rs-4490414/v1
Open publication

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