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Article

Causal Associations of Circulating Lipids with Osteoarthritis: A Bidirectional Mendelian Randomization Study.

Nutrients - 22 Mar 2022

Meng Hongen, Jiang Li, Song Zijun, Wang Fudi

Abstract excerpt

Osteoarthritis (OA) imposes an increasing social burden due to global activity limitations, especially among the aged. Links between circulating lipids and OA have been reported; however, confounding data from observational studies have hindered causal conclusions. We used Mendelian randomization (MR) approach to evaluate the genetic causal effects of circulating apolipoproteins and lipoprotein lipids on OA risk....

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Identifiers

PMID: 35405941
DOI: 10.3390/nu14071327
PMCID: PMC9000847

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