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Article

Causal factors for osteoarthritis risk revealed by mendelian randomization analysis.

Aging clinical and experimental research - 22 Aug 2024

Luo Qingfeng, Zhang Shiyong, Yang Qiyuan, Deng Yuyi, Yi Hengjing, Li Xingsheng

Abstract excerpt

Osteoarthritis (OA), a prevalent chronic disease among the elderly, presents a complex pathogenesis and currently lacks effective treatment. Traditional observational studies are time-consuming, labor-intensive, susceptible to confounding factors, and cannot establish causal relationships. Mendelian randomization (MR) analysis, leveraging genetic variation to assess causal associations between exposures and...

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Identifiers

PMID: 39172202
DOI: 10.1007/s40520-024-02812-9
PMCID: PMC11341639

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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