Genetic aberrations involved in relapse of pediatric acute myeloid leukemia: A literature review.

doi:10.1111/ajco.13367

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Article

Genetic aberrations involved in relapse of pediatric acute myeloid leukemia: A literature review.

Asia-Pacific journal of clinical oncology - 1 Oct 2021

Zafar Naveera, Ghias Kulsoom, Fadoo Zehra

Abstract excerpt

Globally, 15-20% of all children diagnosed with leukemia suffer from acute myeloid leukemia (AML), a rapidly progressive, clinically and biologically heterogeneous disease leading to the impaired differentiation of myeloid blast cells. Although 80% of patients achieve complete remission after induction chemotherapy, many relapse, negatively affecting overall out comes. The mechanisms underlying relapse have not...

Topics

Child
Humans
Leukemia, Myeloid, Acute
Mutation
Prognosis
Recurrence
Remission Induction

Source

Open in PubMed

Identifiers

PMID: 32573082
DOI: 10.1111/ajco.13367

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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