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Computel: Computation of Mean Telomere Length from Whole-Genome Next-Generation Sequencing Data

29 Apr 2015

Abstract excerpt

Telomeres are the ends of eukaryotic chromosomes, consisting of consecutive short repeats that protect chromosome ends from degradation. Telomeres shorten with each cell division, leading to replicative cell senescence. Deregulation of telomere length homeostasis is associated with the development of various age-related diseases and cancers. A number of experimental techniques exist for telomere length...

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Share to Mitochondrial Function and Pathology
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PMID: 25923330
DOI: 10.1371/journal.pone.0125201

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