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Article

Exploring the genetic diversity pattern of PvEBP/DBP2: A promising candidate for an effective Plasmodium vivax vaccine.

Acta tropica - 1 Jul 2024

Hernández-Zambrano Laura J, Alfonso-González Heliairis, Buitrago Sindy P, Castro-Cavadía Carlos J, Garzón-Ospina Diego

Abstract excerpt

Malaria remains a public health challenge. Since many control strategies have proven ineffective in eradicating this disease, new strategies are required, among which the design of a multivalent vaccine stands out. However, the effectiveness of this strategy has been hindered, among other reasons, by the genetic diversity observed in parasite antigens. In Plasmodium vivax, the Erythrocyte Binding Protein (PvEBP,...

Topics

Plasmodium vivax
Genetic Variation
Protozoan Proteins
Humans
Malaria Vaccines
Malaria, Vivax
Antigens, Protozoan
Colombia
Phylogeny
Receptors, Cell Surface

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38685340
DOI: 10.1016/j.actatropica.2024.107231

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-38685340-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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